In patients with atopic dermatitis, there is a violation of the synthesis of fatty acids, so diet therapy should include nutritional supplements saturated with fatty acids: vegetable oils (olive, sunflower, soybean, corn, etc.), linoleic and linolenic acids (vitamin F-99). Drug therapy in the treatment of atopic dermatitis includes the use of tranquilizers, antiallergic, detoxifying and anti-inflammatory drugs. The most important in the practice of treatment are drugs with antipruritic action - antihistamines (antiallergic) drugs and tranquilizers. Antihistamines are used to relieve itching and swelling of the skin, as well asin other atopic conditions (bronchial asthma, hay fever).
A significant drawback of first-generation antihistamines (mebhydrolin, clemastine, chloropyramine, hifenadine) is the rapidly developing addiction of the body. Therefore, the change of these drugs must be carried out every week. A pronounced sedative effect, leading to a decrease in concentration and impaired coordination of movements, does not allow the use of first-generation drugs in the pharmacotherapy of people in certain professions (drivers, students, etc.).
Significantly safer in the treatment of atopic dermatitis in persons with comorbidities is the use of second-generation antihistamines (loratadine, ebastine, astemizole, fexofenadine, cetirizine). They do not develop addiction, there is no atropine-like side effect. Loratadine is currently the most effective and safest antihistamine used in the treatment of atopic dermatitis.
Due to the atropine-like side effects, a number of diseases are a contraindication to the use of Ampicillin drugs: glaucoma, bronchial asthma, prostate adenoma.
To alleviate the condition of patients with severe attacks of itching, drugs that affect the autonomic and central nervous system (hypnotics, sedatives, tranquilizers) are prescribed.
The use of corticosteroid drugs (methiprednisolone or triamcinolone) is indicated for limited and widespread skin lesions, as well as for severe, unbearable itching that is not relieved by other medications. Corticosteroids are prescribed for several days to stop an acute attack and are canceled with a gradual decrease in the dose.
In severe atopic dermatitis and severe symptoms of intoxication, intravenous infusion of infusion solutions is used: dextran, salts, saline, etc. In some cases, it is advisable to carry out hemosorption or plasmapheresis - methods of extracorporeal blood purification.
With the development of purulent complications of atopic dermatitis, it is reasonable to use broad-spectrum antibiotics in age dosages: erythromycin, doxycycline, metacycline for 7 days. When a herpes infection is attached, antiviral drugs are prescribed - acyclovir or famciclovir.